Cholesterol Confusion: Dave Feldman on Lean Mass Hyper-responders
Episode Overview
High LDL cholesterol isn't always bad, especially in certain low-carb dieters. Lean Mass Hyper-responders have a unique lipid profile: high LDL, high HDL, and low triglycerides. Transcytosis plays a crucial role in how LDL particles move through the body. The pizza box analogy helps explain the function of lipoproteins. Current medical advice on cholesterol may need revisiting based on new research.
I feel like anytime I'm getting deeper in, I'm just dumbfounded at how much more of an advanced network this is than anything I had ever written code for
Ever wondered if high cholesterol is really as bad as everyone says? In this episode of 'Recovery and Transformation', host Sameer Dossani sits down with Dave Feldman, an engineer turned lipid researcher, to unpack the complexities of cholesterol. Feldman dives into the concept of the Lean Mass Hyper-responder phenotype, a term he coined to describe people with high LDL, high HDL, and low triglycerides, often seen in those on low-carb diets.
The conversation kicks off with the basics but soon ventures into deeper scientific territory, discussing topics like transcytosis and the role of native LDL in heart disease. Feldman uses relatable analogies, like comparing lipoproteins to pizza boxes, to explain these complex mechanisms in a way that's easy to grasp. If you're curious about how cholesterol works or questioning what you've been told about it, this episode offers a fresh perspective.
By the end, you'll be pondering whether current medical advice on cholesterol needs a serious update. Dive in for an eye-opening chat that might just change how you think about your health.