American Society of Addiction Medicine
American Society of Addiction Medicine
Lead: Outpatient Low-Dose Initiation of Buprenorphine for People Using Fentanyl
Lead: Outpatient Low-Dose Initiation of Buprenorphine for People Using Fentanyl
Lead: Outpatient Low-Dose Initiation of Buprenorphine for People Using Fentanyl
Tuesday 4th February 2025
Explore the latest research on outpatient low-dose buprenorphine initiation for fentanyl users and other key addiction medicine topics.
7 minutes
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American Society of Addiction Medicine
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Get the buttons here!Outpatient Low-Dose Buprenorphine: New Insights for Fentanyl Users
Episode Overview
- Low-dose buprenorphine initiation aims to reduce precipitated withdrawal risk for fentanyl users.
- Celebrate Recovery supports those with substance use disorders through a Christian framework.
- Cannabis consumption methods vary between medical and non-medical users.
- Optimal length of stay for veterans in SUD treatment ranges from 35 to 49 days.
- Extended-release naloxone offers potential for prolonged protection against opioid overdose.
The accumulation of fentanyl in fat is likely responsible for the risk of precipitated withdrawal when buprenorphine is initiated
This episode of 'This Week in Addiction Medicine' takes a deep dive into the outpatient low-dose initiation (LDI) of buprenorphine for individuals using fentanyl. The episode highlights a study from JAMA Network Open, which examines the accumulation of fentanyl in fat and its impact on the risk of precipitated withdrawal when buprenorphine is introduced. With 126 individuals making 175 LDI attempts, the study provides valuable insights into the success rates and challenges faced by those attempting this protocol.
The episode also touches on the effectiveness of different LDI protocols and their retention rates over a month-long period. In addition to the lead story, the podcast covers a range of other fascinating topics. You'll hear about Celebrate Recovery, a Christian mutual help organisation, and its role in supporting those with substance use disorders.
The episode also explores trends in cannabis consumption methods among medical and non-medical users, the optimal length of stay for veterans in substance use disorder residential treatment, and the rising prevalence of sedative, hypnotic, or anxiolytic use disorders among adolescents and young adults on Medicaid. Moreover, the discussion extends to the relationship between cannabis laws and opioid misuse, highlighting a study that examines whether legalisation impacts opioid use disorder rates.
The episode concludes with an intriguing look at a novel extended-release naloxone designed to offer prolonged protection against opioid overdose, and a review of the federal legal landscape regarding the prescription of psychostimulants for stimulant use disorder treatment. If you're keen on staying updated with the latest research and developments in addiction medicine, this episode is packed with valuable information and expert insights. Tune in to learn more about these critical issues and their implications for treatment and recovery.