Epigenetic Insights into Methamphetamine Dependence and More
Episode Overview
Methamphetamine dependence is linked to specific epigenetic changes. Cannabis use has increased in Canada post-legalisation. Offering buprenorphine during incarceration may improve post-release outcomes. Primary care can effectively manage opioid use disorder with swift medication initiation. Patients face various hurdles when discontinuing buprenorphine treatment.
Hypomethylation of the CNOT1 and PUM1 genes could be tied to symptoms like psychosis.
Ever wondered how methamphetamine dependence affects the brain at a genetic level? This episode of 'This Week in Addiction Medicine from ASAM' dives into a groundbreaking study that explores the epigenetic changes associated with methamphetamine use. Researchers found 13 regions with differential methylation, shedding light on the biological changes linked to addiction. Particularly intriguing are the hypomethylation of the CNOT1 and PUM1 genes, which could be tied to symptoms like psychosis, commonly seen in mood disorders and schizophrenia.
The episode also covers a variety of other studies that touch on different aspects of addiction and its treatment. From the rise in cannabis use post-legalisation in Canada to the benefits of offering buprenorphine during incarceration, there's a wealth of information here. The discussion on how primary care can effectively address opioid use disorder offers practical insights for healthcare providers. You'll also hear about patients' perspectives on discontinuing buprenorphine treatment, highlighting logistical hurdles and personal challenges.
Plus, there's an intriguing piece on the potential of psychedelics as a treatment for addiction, urging modern medicine to learn from indigenous practices. This episode is packed with research findings that not only inform but also provoke thought about the future of addiction treatment. Whether you're in the medical field or have a personal interest in addiction recovery, this episode offers valuable insights and practical advice.
Don't miss out on these compelling discussions that could change how we understand and treat addiction.