The Impact of Regular Opioid Use on Dementia Risk
Episode Overview
Regular opioid use linked to higher dementia risk. Dose-dependent relationship found in opioid prescriptions. Weaning buprenorphine in pregnancy reduces neonatal withdrawal. Drugs hijack brain pathways meant for natural rewards. Stigma impacts post-overdose treatment decisions.
Regular opioid use was associated with increased risk of incident dementia, with a dose-dependent response.
Ever wondered about the long-term effects of regular opioid use on brain health? This episode of 'This Week in Addiction Medicine from ASAM' dives into a fascinating cohort study published in the American Journal of Geriatric Psychiatry. Researchers examined the link between regular opioid use in chronic pain patients and the development of dementia over 15 years. The findings are pretty eye-opening: those using opioids regularly had a higher risk of developing dementia compared to those using non-opioid analgesics.
The risk increased with the number of prescriptions, making this a crucial listen for anyone concerned about opioid use and brain health. But that's not all! The episode also covers a study from the Journal of Maternal Fetal and Neonatal Medicine on weaning buprenorphine in pregnant patients. The results? Pregnant women who reduced their buprenorphine doses had fewer instances of neonatal opioid withdrawal syndrome, highlighting an important approach to managing opioid use during pregnancy.
Another intriguing study discussed comes from Science, focusing on how drugs like morphine and cocaine hijack brain pathways meant for natural rewards like hunger and thirst. The episode rounds out with a look at various articles tackling topics from low-level alcohol consumption to untreated psychiatric disorders among caregivers, and the stigma faced by patients refusing post-overdose treatment. With such a diverse range of studies and findings, this episode is packed with valuable information for anyone interested in addiction medicine.
Whether you're a healthcare professional, someone affected by addiction, or just curious about these topics, there's something here for you. Tune in to stay informed and make sense of the complex world of addiction medicine.