Dr. Kurt Devine and Dr. Heather Bell
Dr. Kurt Devine and Dr. Heather Bell
Episode 99 - Buprenorphine Ceiling Effect
Episode 99 - Buprenorphine Ceiling Effect
Episode 99 - Buprenorphine Ceiling Effect
Thursday 14th April 2022
Learn why buprenorphine doesn't cause respiratory depression overdoses despite its high morphine equivalent in 'The Addiction Connection'.
18 minutes
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Dr. Kurt Devine and Dr. Heather Bell
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Understanding Addiction & Recovery
Navigating Alcohol Dependency
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Family Recovery from Addiction
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Get the buttons here!Buprenorphine's Ceiling Effect: A Deep Dive with Drs. Bell and DeVine
Interestingly, what they found was that at 32 milligrams, and they didn't find this, this is actually the calculated. And we're talking from a morphine-equivalent standpoint, right, which is why, an aside, we don't calculate buprenorphine into the morphine-equivalent total Daily dose. But remember, it's a partial agonist, right, which is why they did this study.
Have you ever wondered why buprenorphine, despite its high morphine equivalent, doesn’t lead to respiratory depression overdoses? In this fascinating episode of 'The Addiction Connection', Drs. Heather Bell and Kurt DeVine tackle this very question. They break down the concept of the buprenorphine ceiling effect, a phenomenon that can be tricky to explain to both patients and healthcare professionals alike.
Through data and research, the doctors clarify how the partial agonist properties of buprenorphine contribute to its safety, even at higher doses. They also address the practical aspects of managing patient cravings and the overall benefits of this medication in addiction treatment. Whether you're a medical student, a practicing provider, or someone personally touched by addiction, this episode offers valuable insights into the science behind buprenorphine. It’s an engaging and educational listen that makes complex medical topics accessible and understandable.