Rats, Dopamine, and Addiction: Unpacking the Psychomotor Stimulant Theory
You see the relationship now between locomotor activity, dopamine levels and affect. Those of you that believe in affect-driven models of addiction, which are very popular today- and I'm not saying they're wrong, I'm just not necessarily locked into them, like other people are.
Why are scientists so fascinated by rats running around in a box? In this episode of the ASNet Primer on Psychopharmacology, Dr. Michael Bozarth unravels the mystery behind these furry little test subjects and their significant role in addiction science. The focus is on the Psychomotor Stimulant Theory of Addiction, a concept that links locomotor activity, brain dopamine levels, and human mood and affect. Dr.
Bozarth dives into how dopamine is not just a chemical but a key player in locomotor activity, mood regulation, reward, and positive reinforcement. By studying the behavior of rats, researchers can gain insights into chronic drug effects, compare different substances, and analyze various dosages. This episode lays down the groundwork for understanding the intricate relationship between neuroscience and addiction.
If you're keen on decoding the science behind addiction, this podcast offers a treasure trove of educational content designed for both academic and professional audiences. So, grab your headphones and get ready to explore how tiny rats can provide big answers in the field of addiction science.