UK Health Radio Podcast
UK Health Radio Podcast
9: The Onco’Zine Brief with Peter Hofland, Ph.D - Episode 9
9: The Onco’Zine Brief with Peter Hofland, Ph.D - Episode 9
9: The Onco’Zine Brief with Peter Hofland, Ph.D - Episode 9
Sunday 17th December 2023
Join Dr. Steven Spellman on The Onco’Zine Brief as he discusses cryopreservation's impact on cell grafts and cancer treatment outcomes during COVID-19.
47 minutes
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Get the buttons here!Cryopreservation in Cancer Treatment: Insights from Dr. Steven Spellman
Episode Overview
- The study compares transplants performed before and during the COVID-19 pandemic, revealing no impact on overall survival and GVHD-free relapse-free survival with cryopreserved grafts
- Cryopreserved grafts showed an increased risk of relapse and reduced disease-free survival, but a decreased risk of chronic GVHD
- Dr. Spellman discusses the impact of logistical complexities during the pandemic and potential future research directions
- Observational studies and potential benefits of cryopreserved grafts when fresh grafts are not feasible
- Insights into the risks and benefits of cryopreservation in cellular therapy and transplant practice
Ultimately, the risks are there, but the risks of not proceeding to transplant likely far outweigh the use of a cryopreserved graft versus a fresh graft.
How did the COVID-19 pandemic affect cancer treatments involving cell grafts? In this episode of The Onco’Zine Brief, Peter Hofland, Ph.D., chats with Dr. Steven Spellman, Vice President and Senior Scientific Director at Be The Match and the Center for International Blood and Marrow Transplant Research. Dr. Spellman delves into the fascinating world of cryopreservation and its impact on hematopoietic cell grafts during these challenging times.
The discussion centers on a study comparing transplants from early 2019 to those during the pandemic in 2020. You'll hear about the unexpected findings that cryopreserved grafts didn't affect overall survival or GVHD-free relapse-free survival but did show an increased risk of relapse and reduced disease-free survival. Interestingly, there was a decreased risk of chronic GVHD with these grafts. Dr. Spellman also touches on the complexities faced during the pandemic and what future research might look like.
This episode is perfect for anyone curious about the intricacies of cancer treatment and how global events can shape medical outcomes.