High Doses of Buprenorphine: Changing the Game in Opioid Treatment
Episode Overview
Higher doses of buprenorphine may lead to reduced urgent healthcare utilization. Overdose deaths have significantly declined recently. Robert F. Kennedy Jr.'s recovery journey offers valuable insights. FDA's recommended buprenorphine dose might be insufficient for some patients. Real-world data suggests higher doses can improve patient outcomes.
I used to think like early in my career, like when someone needed more than 16 mg, I would look at that partial agonist curve of receptor saturation and be like, there's nothing more that you're getting after 16 mg.
If you're keen to stay updated with the latest research in addiction medicine, this episode of Addiction Medicine Journal Club is a must-listen. Dr. Sonya Del Tredici and Dr. John Keenan dive into a fascinating discussion on the implications of higher daily doses of buprenorphine, especially in the context of the ongoing fentanyl crisis. They explore an article from JAMA Network Open, which examines how doses higher than the FDA-recommended 16 mg per day can impact urgent healthcare utilization.
The episode also covers the significant decline in overdose deaths and Robert F. Kennedy Jr.'s experiences with recovery, adding a personal touch to the scientific discussion. The hosts bring their unique blend of expertise and humour, making complex topics accessible and engaging. Whether you're a healthcare professional or someone interested in addiction recovery, you'll find valuable insights and practical takeaways.
Tune in to understand how higher doses of buprenorphine could change the landscape of opioid use disorder treatment and what it means for patients and healthcare providers alike.