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Root Medicine

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  • #32 - Dr. Dalibor Sames: Why We Need Ibogaine Analogues

#32 - Dr. Dalibor Sames: Why We Need Ibogaine Analogues

Thursday 20th June 2024

Dr. Dalibor Sames discusses the development of safer ibogaine analogues and their potential to revolutionise addiction treatment.
58 minutes
Informative
Inspiring
Hopeful
Educational
Engaging

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Root Medicine
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The Future of Addiction Treatment: Dr. Dalibor Sames on Ibogaine Analogues

Episode Overview

  • Dr. Sames' journey from chemistry admiration to pharmaceutical innovation.
  • The potential of ibogaine analogues to reduce cardiac risks.
  • How small molecular changes can significantly impact drug effects.
  • The role of neuroplasticity in addiction treatment.
  • Future directions for psychedelic medicine in mental healthcare.
Each layer we discover, we'll talk. Let's do it. I'm in.
In this episode of 'Root Medicine', Amanda Siebert sits down with Dr. Dalibor Sames, a professor of chemistry at Columbia University, to discuss the fascinating world of ibogaine and its analogues. Dr. Sames shares his journey from developing an 'aesthetic admiration' for the molecular structure of ibogaine to founding two pharmaceutical companies aimed at creating safer and more effective ibogaine analogues.
The conversation dives into the science behind these compounds, their potential therapeutic benefits, and the innovative ways they could reshape mental healthcare and addiction treatment. Dr. Sames explains how small changes in the molecular structure of ibogaine can lead to significant differences in its effects, potentially reducing the cardiac risks associated with the drug. This episode offers a blend of scientific insight and personal passion, making complex topics accessible and engaging.
Whether you're curious about the future of psychedelic medicine or looking for new perspectives on addiction treatment, this episode is packed with valuable information and thought-provoking ideas. Tune in to learn how ibogaine analogues could revolutionise mental health treatment and offer new hope for those struggling with addiction.