A. M.
A.M.
3.5_Alternative Botanical Sources of Ibogan Alkaloids_Felix Krengel
3.5_Alternative Botanical Sources of Ibogan Alkaloids_Felix Krengel
3.5_Alternative Botanical Sources of Ibogan Alkaloids_Felix Krengel
Saturday 27th February 2021
Join Dr. Felix Krengel on 'Iboganautics' as he explores new sources of ibogan alkaloids and their visionary potential.
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Get the buttons here!New Frontiers in Ibogan Alkaloids: Dr. Felix Krengel's Insights
I think plants like Tabernae montana species have a huge potential for producing semi-synthetic ibogaine, especially because in Mexico, at least the species I've worked with, they're not endangered species.
Imagine discovering new ways to harness the power of a plant known for its profound effects. That's exactly what Dr. Felix Krengel is doing. Recently completing his PhD in biological sciences at the Universidad Nacional Autónoma de México, Dr. Krengel dives into his groundbreaking research on alternative botanical sources of ibogan alkaloids in this episode of 'Iboganautics'. His work focuses on the Apocynaceae plant family, specifically Mexican species that produce ibogan-type alkaloids like coronaridine, ibogamine, voacangine, and ibogaine.
With only a handful of labs worldwide exploring this frontier, Dr. Krengel's insights are truly pioneering. The conversation kicks off with a deep dive into the differences between primary and secondary metabolites and the various plant families, genera, and species that produce these alkaloids. Dr. Krengel explains how these plants use secondary metabolites as a defense mechanism and how environmental stress can influence alkaloid production.
He also sheds light on the economic viability of extracting ibogaine from non-Tabernanthe iboga species like Voacanga. As the discussion unfolds, Dr. Krengel addresses the ecological pressures on iboga plants due to overexploitation and the resulting market for 'fake iboga'. He suggests that Mexican Tabernaemontana species offer a promising alternative for semi-synthetic ibogaine production, especially since they are not endangered. Dr.
Krengel's expertise doesn't stop at botany; he delves into the biochemistry of these plants, discussing the four main alkaloids they produce and their potential visionary effects. He emphasizes the need for human studies to fully understand these auxiliary alkaloids' capabilities. The episode also explores advanced topics like genetic engineering and bioreactors, proposing that genetically modified yeast could be a game-changer in producing these compounds under controlled conditions.
This episode is a treasure trove of information for anyone interested in the scientific and ecological aspects of iboga. Whether you're a seasoned researcher or just curious about this fascinating plant, Dr. Krengel's insights offer a fresh perspective on the future of ibogan alkaloids.