Sleep, Dreams, and Ibogaine: A Neuroscientist's Insight
Ibogaine would be like a sleep deprivation drug and perhaps their effects would come out of the sleep deprivation. And then you could actually have the opposite or like the opposite hypothesis, that is, that ibogaine would actually induce some dream-like state.
What happens when a powerful psychedelic like ibogaine interacts with our sleep? Joaquín González, a PhD candidate in neuroscience from Uruguay, dives deep into this question. His research, conducted at the University of the Republic in Montevideo, explores how ibogaine impacts sleep and wakefulness, offering a unique perspective on this intriguing substance. Joaquín's study, titled 'Ibogaine Acute Administration in Rats Promotes Wakefulness, Long-Lasting REM Sleep Suppression, and a Distinctive Motor Profile', is the backbone of this episode.
He explains how low doses of ibogaine can stimulate the mind, while higher doses lead to visionary experiences. But here's the twist: ibogaine suppresses REM sleep, the stage where dreams typically occur, yet it induces dream-like states. How can that be? Joaquín unpacks this paradox and discusses the broader implications for addiction treatment. He also touches on potential risks like prolonged sleep deprivation and ibogaine toxicity.
This episode isn't just for science buffs; it's for anyone curious about the mysterious ways psychedelics can alter our consciousness and bodily functions. Joaquín's personal experiences with ibogaine add an extra layer of depth, making this a must-listen for anyone interested in the intersection of neuroscience and psychedelics.